The BIO-WORLD Serum Abundant Protein Removal (SAPR ) kit (catalog#515911) removes four highly abundant proteins from human serum and plasma.  Transferrin removal kit specifically removes transferrin from serum samples. The high affinity-based columns contain Separopore™ -matrix coupled with antibodies against this major serum protein and include buffers for binding and elution. The kit is designed to provide specific, and complete removal of transferrin protein, which is one of the abundant proteins in human serum.
The presence of abundant proteins in human serum and plasma often masks the detection of low-abundant proteins of interest that serve as biomarkers for disease when being studied by 2D gel electrophoresis or LC/MS. After depletion of high-abundant proteins, serum samples consist of an enriched pool of low-abundant proteins that can be further studied without significant interferences with abundant proteins.
The BIO-WORLD SAPR-HSA kit (catalog #515912) removes the highly abundant protein Human Serum Albumin only. This protein can also be removed by using Blue-Separopore™ (catalog #506480)