Close

Description

Fractionated Pisum sativum lectin or agglutinin (PSA) is a heterodimer that consists of four subunits. It has a carbohydrate specificity towards ?-linked mannose-containing oligosaccharides. It�s hemagglutinating activity can be inhibited by glucose, mannose, and sucrose. It does not have a blood group specificity. The N-terminal sequence of the lectin has shown some degree of homology compared to lectins from other legume species. Pisum sativum lectin has also shown mitogenic effect toward murine splenocytes and could inhibit activity of HIV-1 reverse transcriptase. PSA is often used to differentiate virally transformed from normal cells. Calcium and manganese ions are required for activity

Storage Instruction: To prevent degradation and avoid repeated freeze-thaw cycles, aliquot your product into small, single-use volumes and store them at -20°C

Properties

Shelf life

2 years

Storage Temperature

-20°C

ECCN #

EAR99

Appearance form

Lyophilized Powder

Molecular Weight

50 kDa

Abbreviation (Lectins Only):

PSA/PSL

Source

Pea

Blood Group Specificity

Rabbit non-specific

Carbohydrate Specificity

D-Mannose, D-Glucose

Conjugate/Tag/Matrix

None

Inhibitory Carbohydrate

D-Mannose, D-Glucose

Divalent Ions

Ca++, Mn++

Mitogenic Activity

Yes