Blasticidin S HCl Solution, 10mg/mL, Sterile

Blasticidin S is a nucleoside antibiotic isolated from Streptomyces griseochromogenes. It is a potent inhibitor of protein synthesis in both prokaryotic and eukaryotic cells. Blasticidin S acts by inhibiting peptide bond formation by the ribosome. Blasticidin S is used for the prevention of contamination of cell cultures. The recommended working concentration ranges from 2 to 20 µg/ml depending on the cell line. Blasticidin, also used in gene selection. Resistance to blasticidin is conferred by the blasticidin resistance gene from bacillus cereus (bsr). Bsr codes for blasticidin deaminase.

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