Agaricus bisporus Lectin (ABA/ABL) - Alexa Fluor 594

Agaricus bisporus Lectin (ABA/ABL) is isolated from edible mushroom and purified by using GalNAc sepharose 4B. This Lectin is composed of four subunits with slightly different amino acid sequences and glycosylation specificity. ABA/ABL Lectin has high affinity for galactose--1,3-N-acetylgalacto samine (Gal--1,3-GalNAc; also known as T-antigen disaccharide) and galactose--1,3-N acetylglucosamine, but does not bind to monosaccharides. ABA is a potent mitogen for T cells and binds to serum protein IgA. Agaricus bisporus has an anti-proliferative effect on cancerous cells. ABA can be internalized by clathrin-coated vesicles after binding to surface glycoproteins, thus making ABA an inhibitor of its nuclear import of signal-dependent proteins. Pure Lectin was conjugated with Alexa Fluor™ 594, is a red fluorescent dye with an excitation 590 to maximum emission 617 nm. The ABA Alexa Fluor™ 594 conjugate is ideal for immunofluorescence, immunohistochemistry and immunocytochemistry. Alexa Fluor™ 594 dye is high water soluble and pH-stable (pH 4 to pH 10), ensuring reliable performance across various conditions. This lectin-dye conjugate is optimized for cellular labeling and detection, making it a valuable tool for enhancing sensitivity in research applications.

Application: Glycobiology, Immunofluorescence, Immunohistochemistry, Immunocytochemistry.

Recommended usage: Recommended concentration 5-20 ug/ml in 1XPBS.

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