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Description

Synonyms: ARF-1, ADP-ribosylation factor 1.

ARF1 is a small guanine nucleotide-binding protein that increases the enzymatic activities of cholera toxin. ARF1 is necessary and ubiquitous in eukaryotes. ARF1 takes part in vesicular transport and functioning via phospholipase D activation. ARF1 is involved in membrane traffic and organelle integrity which are closely tied to their reversible association with membranes and distinct interactions with membrane phospholipids.

Description: ARF1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 201 amino acids (1-181 a.a.) and having a molecular mass of 22.8 kDa. The ARF1 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Source: Escherichia coli

Physical Appearance: Sterile filtered colorless solution

Formulation: The ARF1 protein solution (1mg/ml) containing 20mM Tris-HCl pH-8, 1mM DTT, 0.1M NaCl & 20% glycerol.

Stability: ARF1 Human although stable at 4°C for 1 week, should be stored desiccated below -18°C.

Please prevent freeze thaw cycles.

Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MGNIFANLFK GLFGKKEMRI LMVGLDAAGK TTILYKLKLG EIVTTIPTIG FNVETVEYKN ISFTVWDVGG QDKIRPLWRH YFQNTQGLIF VVDSNDRERV NEAREELMRM LAEDELRDAV LLVFANKQDL PNAMNAAEIT DKLGLHSLRH RNWYIQATCA TSGDGLYEGL DWLSNQLRNQ K.

Usage: Bio-world products are for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products: ARF4 Human, ARF5 Human, ARF6 Human

Properties

Storage Temperature

-20°C

Purity

Greater than 90.0% as determined by SDS-PAGE