ADP-Ribosylation Factor-Like 1 Human (Recombinant)

Synonyms: ARFL1

ARL1 is part of the ARL (ADP-ribosylation factor-like) family of proteins, which are structurally associated to ADP-ribosylation factors (ARFs). ARFs, described as activators of cholera toxin (CT) ADP-ribosyltransferase activity, control intracellular vesicular membrane trafficking, and stimulate a phospholipase D (PLD) isoform. ARL1 is a weak stimulator of PLD and CT in a phospholipid dependent manner. ARL1 is a GTP-binding protein that has low efficiency as allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. ARL1 is involved in the Golgi apparatus.

Description: ARL1 Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 201 amino acids (1-181 a.a.) and having a molecular mass of 22.5 kDa. The ARL1 is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Source: Escherichia coli

Physical Appearance: Sterile filtered colorless solution

Formulation: 0.25mg/ml solution containing 20mM Tris pH-8, 1mM DTT & 10% glycerol.

Stability: ARL1 Human although stable at 4C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles.

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGGFFSSIFS SLFGTREMRI LILGLDGAGK TTILYRLQVG EVVTTIPTIG FNVETVTYKN LKFQVWDLGG QTSIRPYWRC YYSNTDAVIY VVDSCDRDRI GISKSELVAM LEEEELRKAI LVVFANKQDM EQAMTSSEMA NSLGLPALKD RKWQIFKTSA TKGTGLDEAM EWLVETLKSR Q

Usage: Bio-world products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products: ARL11 Human, ARL2 Human