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Description

Synonyms

Annexin A9, Annexin-9, Annexin-31, Annexin XXXI, Pemphaxin, ANXA9, ANX31.

The annexins are a family of calcium-dependent phospholipid-binding proteins. Members of the annexin family contain 4 internal repeat domains, each of which includes a type II calcium-binding site. The calcium-binding sites are required for annexins to aggregate and cooperatively bind anionic phospholipids and extracellular matrix proteins. The most striking feature of annexin 31 is a complete ablation of all four homologous type II calcium-binding sites in the conserved tetrad core. Although all 4 type II calcium-binding sites in annexin 31 contained amino acid substitutions that ablated their function, structural analysis suggests that the conserved putative ion channel formed by the tetrad core is intact.

Description

ANXA-9 Human Recombinant produced in E.coli is a non-glycosylated, polypeptide chain containing amino acids (1-338) and having a total molecular mass of 38.9 kDa. ANXA9 contains T7 tag at N-terminus and is purified by proprietary chromatographic techniques.

Source

Escherichia coli

Physical Appearance

Sterile Filtered clear solution.

Formulation

Annexin-9 at a concentration of 0.1mg containing 10mM Tris, pH 8.0, 0.1% Triton X-100 and 0.002% NaN3.

Stability

Annexin-9 although stable at 4°C for 1 week, should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Applications

• ELISA
• MS
• Western Blotting.

Usage

Bio-world products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

ANXA1 Human, ANXA11 Human, ANXA13 Human, ANXA2 Human, ANXA3 Human, ANXA4 Human, ANXA5 Human, ANXA6 Human, ANXA7 Human, ANXA8 Human

Properties

Storage Temperature

-20°C

Purity

Greater than 95.0% as determined by SDS-PAGE