Copper Transport Protein ATOX1 Human (Recombinant)

Synonyms

Antioxidant protein 1, ATX1, HAH1, Copper transport protein ATOX1, Metal transport protein ATX1, ATOX1, MGC138453, MGC138455.

ATOX1 is a metal transport protein that is part of the ATX1 family. ATOX1 is a copper chaperone that takes part in cellular antioxidant defense and can bind and deliver cytosolic copper to the copper ATPase proteins in the trans-Golgi network for later incorporation to the ceruloplasmin. ATOX1 plays a role as an antioxidant against superoxide and hydrogen peroxide, and consequently, takes an important part in cancer carcinogenesis. Because of ATOX1 cytogenetic location, the gene can be a good a candidate gene for 5q-syndrome.

Description

ATOX1 Human Recombinant produced in E. coli is a single, non-glycosylated, polypeptide chain containing 88 amino acids (1-68 a.a.) and having a molecular mass of 9.5kDa. ATOX1 is fused to a 20 amino acid His Tag at N-terminus and purified by proprietary chromatographic techniques.

Source

Escherichia coli

Physical Appearance

Sterile filtered colorless solution.

Formulation

ATOX1 solution containing 20mM Tris pH-8, 1mM DTT and 10% glycerol.

Stability

ATOX1 Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MPKHEFSVDM TCGGCAEAVS RVLNKLGGVK YDIDLPNKKV CIESEHSMDT LLATLKKTGK TVSYLGLE

Usage

Bio-world products are furnished for LABORATORY RESEARCH USE ONLY. They may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.