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Description

Synonyms

DnaJ homolog subfamily B member 6, HHDJ1, Heat shock protein J2, HSJ-2, MRJ, MSJ-1, DNAJB6, HSJ2, MSJ1, DJ4, DnaJ, MGC1152, FLJ42837, MGC117297, DKFZp566D0824.

DnaJ homolog subfamily B member 6 (DNAJB6) belongs to the DNAJ protein family. The DNAJ family members are characterized by a highly conserved amino acid stretch known as the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. DNAJB6 may also play a role in polyglutamine aggregation in specific neurons.

Description

DNAJB6 Human Recombinant fused with a 23 amino acid His tag at N-terminus produced in E. coli is a single, non-glycosylated, polypeptide chain containing 349 amino acids (1-326 a.a.) and having a molecular mass of 38.5kDa. The DNAJB6 is purified by proprietary chromatographic techniques.

Source

Escherichia coli

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The DNAJB6 solution (0.25 mg/ml) contains 20mM Tris-HCl buffer (pH8.0), 0.2M NaCl, 5mM DTT and 30% glycerol.

Stability

DNAJB6 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSMVDYYEV LGVQRHASPE DIKKAYRKLA LKWHPDKNPE NKEEAERKFK QVAEAYEVLS DAKKRDIYDK YGKEGLNGGG GGGSHFDSPF EFGFTFRNPD DVFREFFGGR DPFSFDFFED PFEDFFGNRR GPRGSRSRGT GSFFSAFSGF PSFGSGFSSF DTGFTSFGSL GHGGLTSFSS TSFGGSGMGN FKSISTSTKM VNGRKITTKR IVENGQERVE VEEDGQLKSL TINGVADDDA LAEERMRRGQ NALPAQPAGL RPPKPPRPAS LLRHAPHCLS EEEGEQDRPR APGPWDPLAS AAGLKEGGKR KKQKQREESK KKKSTKGNH

Usage

Bio-world products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

DNAJB11 Human, DNAJB2 Human, DNAJB8 Human

Properties

Storage Temperature

-20°C

Purity

Greater than 85.0% as determined by SDS-PAGE