Endoplasmic Reticulum Protein 44 Human (Recombinant)

Synonyms

PDIA10, TXNDC4, ER protein 44.

ERP44 is an endoplasmic reticulum chaperone that takes part in thiol-dependent retention of the primary secretory pathway, forming mixed disulfides with substrate proteins through its conserved CRFS motif. ERP44 inhibits the calcium channel activity of ITPR1. ERP44 is involved in the control of oxidative protein folding in the endoplasmic reticulum.

Description

ERP44 Recombinant Human produced in E. coli is a single, non-glycosylated polypeptide chain containing 415 amino acids (30-406 a.a.) and having a molecular mass of 48 kDa. The ERP44 is fused to 38 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Source

Escherichia coli

Physical Appearence

Sterile filtered colorless solution.

Formulation

1mg/ml solution containing 20mM Tris-HCL pH-7.5 & 10% glycerol.

Stability

ERP44 Human although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.

Amino Acid Sequence

MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWAGSMEI TSLDTENIDE ILNNADVALV NFYADWCRFS QMLHPIFEEA SDVIKEEFPN ENQVVFARVD CDQHSDIAQR YRISKYPTLK LFRNGMMMKR EYRGQRSVKA LADYIRQQKS DPIQEIRDLA EITTLDRSKR NIIGYFEQKD SDNYRVFERV ANILHDDCAF LSAFGDVSKP ERYSGDNIIY KPPGHSAPDM VYLGAMTNFD VTYNWIQDKC VPLVREITFE NGEELTEEGL PFLILFHMKE DTESLEIFQN EVARQLISEK GTINFLHADC DKFRHPLLHI QKTPADCPVI AIDSFRHMYV FGDFKDVLIP GKLKQFVFDL
HSGKLHREFH HGPDPTDTAP GEQAQDVASS PPESSFQKLA PSEYRYTLLR DRDEL

Usage

Bio-world products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

ERP27 Human