Epstein-Barr Virus (HHV-4) Mosaic p18, (Recombinant)

Recombinant Epstein-Barr Virus (HHV-4) Mosaic

Source: E.Coli

Background: The Epstein-Barr virus (EBV), also called Human herpes virus 4 (HHV-4), is a virus of the herpes family (which includes Herpes simplex virus and Cytomegalo virus. On infecting the B-lymphocyte, the linear virus genome circularizes and the virus subsequently persists within the cell as an episome. The virus can execute several distinct programs of gene expression which can be broadly categorized as being lytic cycle or laten cycle. The lytic cycle or productive infection results in staged expression of a host of viral proteins with the ultimate objective of producing infectious virions. Formally, this phase of infection does not inevitably lead to lysis of the host cell as EBV virons are produced by budding from the infected cell. THe laten cycle (lysogenic) programs are those that do not result in production of virions. A very limited, distinct set of viral proteins are produced during latent cycle infection. These include Epstein-Barr nuclear antigen EBNA-1, EBNA-2, EBNA-3A, EBNA-3B, EBNA-3C, EBNA-leader protein (EBNA-LP) and latent membrane proteins (LMP)-1, LMP-2A and LMP-2B and the Epstein-Barr encoded RNAs (EBERs).

Description: E.coli derived recombinant artificial mosaic protein contains 2 epitopes from c-end associated in one molecule from the HHV-4 p18 regions.

Purification method: Purified by proprietary chromatographic technique.

Purity: Protein is >95% pure as determined by 10% PAGE (coomassie staining).

Formulation: 50mM Tris-HCl, pH8.0, 60 mM NaCl, 10mM glutathione, and 50% glycerol.

Storage: Protein is shipped at ambient temperature. Upon arrival, Store at -20°C.

Stability: Five years frozen. One month in solution at room temperature.

Specificity: Immunoreactive with sera of EBV-infected individuals.

Application: Antigen in ELISA and Western blots, excellent antigen for detection of HHV-4 (EBV) with minimal specificity problems.

Usage: BioWORLD's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals