Epstein-Barr Virus (HHV-4) p23, (Recombinant)

Recombinant EBV(HHV-4) Capsid Antigen p23

Source: E.Coli

Background: The Epstein-Barr virus (EBV), also called human herpes virus 4 (HHV-4), is a virus of the herpes family (which includes herpers simplex virus and Cytomegalo virus. On infecting the B-lymphocyte, the linear virus genome circularizes and the virus and the virus subsequently persists within the cell as an episome. The virus can exicute several distinct programs of gene expression which can be broadly categorized as bein lytic cycle or latent cycle. The lytic cycle or productive infection results in staged expression of a host of viral proteins with the ultimate objective of producing infectious virions. Formally, this phase of infection does not inevitably lead to lysis of the host cell as EBV virions are produced by budding from the infected cell. The latent cycle (lysogenic) programs are those that do not result in production of virions. A very limited, distinct set of viral proteins are produced during latent cycle infection. These include Epstein-Barr nuclear antigen (EBNA)-1, EBNA-2, EBNA-3A, EBNA-3B, EBNA-3C, EBNA-leader protein (EBNA-LP) and latent membrane proteins (LMP)-1, LMP-2A and LMP-2B and the Epstein-Barr encoded RNAs (EBERs).

Description: E.Coli derived recombinant protein contains (HHV-4) p23 regions, amino acids: (1-162).

Purification method: Recombinant EBV is purified by proprietary chromatographic technique.

Purity: Recombinant EBV is >95% pure as determined by 10% PAGE (coomassie staining).

Formulation: 25mM glycine pH-9.6 and 50% glycerol.

Storage: Recombinant EBV is shipped at ambient temperature. Upon arrival, Store at -20°C.

Stability: Five years frozen. One month in solution at room temperature.

Specificity: Immunoreactive with sera of EBV-infected individuals.

Application: Antigen may be used in: 1.ELISA 2.Western blots 3.Detection of HHV-4 (EBV) with minimal specificity problems.

Usage: BioWORLD's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals