Fatty Acid Binding Protein 2 Human (Recombinant)

Synonyms

Fatty acid-binding protein 2, IFABP, I-FABP, FABPI, FABP-2, Fatty acid-binding protein intestinal, FABP2, MGC133132.

FABP multigene family has almost 20 known members. FABPs are divided into 3 different types: hepatic, intestinal and cardiac which form 14-15 kDa proteins that take part in the uptake, intracellular metabolism and/or transport of long-chain fatty acids. FABPs are involved in the modulation of cell growth and proliferation. Intestinal FABP (FABP2) gene has a polymorphism at codon 54 that identified an alanine-encoding allele and a threonine-encoding allele. Thr-54 protein is associated with increased fat oxidation and insulin resistance. High serum levels of FABP2 is ulcerative colitis indicates ileitis. FABP2 is has part in triglyceride-rich lipoprotein synthesis. FABP2 binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 helps maintain energy homeostasis by functioning as a lipid sensor.

Description

FABP2 Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 132 amino acids and having a molecular mass of 17.3kDa. FABP2 is fused to a 20 aa His tag at N-terminus and purified by standard chromatography techniques.

Source

Escherichia coli

Physical Appearance

Sterile Filtered colorless liquid formulation.

Formulation

FABP2 His-Tag is supplied in 20mM Tris HCl pH 8 and 10% glycerol.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze thaw cycles.

Sequence

MGSSHHHHHH SSGLVPRGSH MAFDSTWKVD RSENYDKFME KMGVNIVKRK LAAHDNLKLT ITQEGNKFTV KESSAFRNIE VVFELGVTFN YNLADGTELR GTWSLEGNKL IGKFKRTDNG NELNTVREII GDELVQTYVY EGVEAKRIFK KD

Usage

Bio-world products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

FABP1 Human, FABP3 Human, FABP3 Human, His, FABP4 Human, FABP4 Human, His, FABP5 Human, FABP5 Human, His, FABP6 Human, FABP6 Human, His, FABP7 Human, FABP7 Human, His, PMP2 Human, PMP2 Human, His