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Hepatitis C Virus NS3 (1450-1643), Biotin Labeled, (Recombinant)

22060151

Hepatitis C Virus NS3 (1450-1643), Biotin Labeled, (Recombinant)

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  SKU Pack Size Price
22060151-1 100 μg $659.52


$659.52

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Description

Hepatitis C Virus NS3 (1450-1643), Biotin Labeled, Recombinant

Introduction HCV is a small 50nm, enveloped, single-stranded, positive sense RNAvirus in the family Flaviviridae.
HCV has a high rate of replication with approximately one trillion particles produced each day in an infected individual. Due to lack of proofreading by the HCV RNA polymerase, the HCV has an exceptionally high mutation rate, a factor that may help it elude the host's immune response. Hepatitis C virus is classified into six genotypes(1-6) with several subtypes within each genotype. The preponderance and distribution of HCV genotypes varies globally. Genotype is clinically important in determining potential response to interferon-based therapy and the required duration of such therapy. Genotypes 1 and 4 are less responsive to interferon-based treatment than are the other genotypes (2, 3, 5 and 6).
Description The E.coli derived recombinant Biotin Labeled protein contains the HCV NS3 immunodominant regions, a.a. 1450-1643, 22 kDa.
The Biotin labeled protein is fused with b-galactosidase (114 kDa) at N-terminus.
Purification Method HCV NS3 Biotin labaled protein was purified by proprietary chromatographic technique.
Purity HCV NS3 Biotin labaled protein is >95% pure as determined by 10% PAGE (coomassie staining).
Formulation 8M urea, 20mM Tris-HCl pH 8.0, 10mM mercaptoethanol.
Storage HCV NS3 Biotin labaled protein is shipped at ambient temperature.
Upon arrival, Store at -20°C.
Stability Five years frozen. One month in solution at room temperature.
Specificity Reactivity with human HCV positive serum undetermined.
Applications HCV NS3 Biotin labaled antigen is suitable for ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems.
Usage BioWORLD's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Properties

Storage Temperature

-20°C