Hepatitis D virus (Recombinant)

Recombinant Hepatitis Delta Virus

Source: E.coli

Background: Hepatitis delta virus (HDV) contains a circular RNA which encodes a single protein, hepatitis delta antigen (HDAg). HDAg exists in two forms, a small form (S-HDAg) and a large form (L-HDAg). S-HDAg can transactivate HDV RNA replication. Post-translational modifications, such as phosphorylation and acetylation, of S-HDAg can modulate HDV RNA replication. The RNAs undergo different forms of posttranscriptional RNA processing. Transcripts of both the genomic RNA and its exact complement, the antigenomic RNA, undergo ribozyme cleavage and RNA ligation. In addition, antigenomic RNA transcripts can undergo 5' capping, 3' polyadenylation, and even RNA editing by an adenosine deaminase

Description: The protein contains the HDV immunodominant regions,amino acids: (1-108)(151-209). Hepatitis D Virus proteins are purified by proprietary chromatographic techniques.

Purification method: Purified from inclusion bodies by proprietary chromatographic technique.

Purity: Recombinant HDV is >90% pure as determined by 10% PAGE (coomassie staining) and RP-HPLC.

Formulation: 1mg/ml containing 10 mM CBB, pH 10.0, NaCl 100mM, 50% glycerol.

Storage: Recombinant HDV is shipped at ambient temperature. Upon arrival, Store at -20C.

Stability: Recombinant HDV is stable 5 years frozen, One month in solution at room temperature.

Specificity: Immunoreactive with sera of HDV-infected individuals

Application: Recombinant HDV Antigen may be used in ELISA and Western blots, excellent for detection of HDV with minimal specificity problems.

Usage: BioWORLD's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.