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Description

Synonyms

Calmodulin, CaM, CALM2, PHKD, CAMII, PHKD2, calmodulin 2, phosphorylase kinase delta.

Calmodulin (CaM) is an intracellular receptor protein for Ca2+-ions. It activates the myosin light chain kinase which is the catalyst of myosin phosphorylation. CaM participates in the activation of enzymes such as cyclic nucleotide- dependent phosphodiesterase, calcineurin, ATPase, Myosin Light Chain Kinases, and CAM kinase.

Description

Calmodulin Human Recombinant full length protein expressed in E. coli, having a Molecular Weight of approximately 16 kDa, the Accession number is NP_001734.

Source

Escherichia coli

Physical Appearance

Sterile Filtered clear solution.

Formulation

Calmodulin at 1mg/ml in 20mM HEPES-KOH, pH7, 50mM NaCl, 1mM EDTA and 1mM DTT.

Activity

Assayed for calcium binding and activation of MLCK.

Stability

Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.

Applications

• ELISA
• Inhibition Assays
• Western Blotting.

Amino Acid Sequence

MADQLTEEQI AEFKEAFSLF DKDGDGTITT KELGTVMRSL GQNPTEAELQ DMINEVDADG NGTIDFPEFL TMMARKMKDT DSEEEIREAF RVFDKDGNGY ISAAELRHVM TNLGEKLTDE EVDEMIREAD IDGDGQ.

Usage

Bio-world products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

CALM2 Human, Calmodulin Antibody

Properties

Storage Temperature

-20°C

Purity

Greater than 90% as determined by SDS-PAGE