Human P-Selectin (Recombinant)

Recombinant Human P-selectin

Source: E.Coli

Background: P-Selectin (Platelet Alpha-Granule Membrane Protein/CD62/Granulocyte Membrane Protein GRMP) belongs to a family of divalent cation-dependent carbohydrate-binding glycoproteins or adhesion molecules. Pselectin is expressed transiently on the surface of activated platelets and endothelial cells. Secreted P-selectin is thought to play a key role in the adhesion of platelets to monocytes and neutrophils during an inflammatory response. Levels of P-Selectin may be elevated in a number of pathological conditions.

Description: Recombinant Human P-Selectin is expressed in E. coli containing 566 amino acids 197-761 fused to an amino terminal hexahistidine tag.

Physical Appearance: Sterile Filtered clear solution.

Formulation: Recombinant Human PSel is supplied in 1x Laemmli Buffer (25mM Tris-HCl pH6.8, 50mM DTT, 1%(w/v) SDS, 0.1%(w/v) Bromophenol Blue and 2.5% Glycerol).

Stability: Store at 4°C if entire vial will be used within 1-2 weeks. Store, frozen at -20°C for longer periods of time. Please avoid freeze-thaw cycles.

Applications: Recombinant P-Selectin can be used directly as a positive control in Western blotting, ELISA, immunoprecipitation and other immunological experiments. The biological activity of this product has not yet been tested.

Purity: Greater than 95% (SDS-PAGE). Single band on Western Blot.

Usage: BioWORLD's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.