Microtubule-Associated Protein 1 Light Chain 3 Alpha Human (Recombinant)

Synonyms

ATG8E, LC3, LC3A, MAP1ALC3, MAP1BLC3, MLP3A.

MAP1LC3A takes part in formation of autophagosomal vacuoles and is one of the light chain subunits that functions together with both MAP1A and/or MAP1B. MAP1LC3A has an important part in neuronal development and in maintaining the balance between neuronal plasticity and rigidity. MAP1LC3A is expressed as two alternatively spliced isoforms that are expressed in testis, brain, heart, liver and skeletal muscle, but are absent in thymus and peripheral blood leukocytes.

Description

MAP1LC3A Recombinant Human produced in E. coli is a single, non-glycosylated polypeptide chain containing 128 amino acids (1-120 a.a.) and having a molecular mass of 15.1 kDa. The MAP1LC3A is fused to 8 amino acid His-Tag at C-terminus and purified by proprietary chromatographic techniques.

Source

Escherichia coli

Physical Appearence

Sterile filtered colorless solution.

Formulation

1mg/ml solution containing 20mM Tris pH-8, 1mM DTT, 0.1M NaCl & 10% glycerol.

Stability

MAP1LC3A Human although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.

Amino Acid Sequence

MPSDRPFKQR RSFADRCKEV QQIRDQHPSK IPVIIERYKG EKQLPVLDKT KFLVPDHVNM SELVKIIRRR LQLNPTQAFF LLVNQHSMVS VSTPIADIYE QEKDEDGFLY MVYASQETFG LEHHHHHH

Usage

Bio-world products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

MAP1LC3B2 Human, MAPRE3 Human, MAPT Human, MAPT Human 381a.a., MAPT Human 383a.a.