Myosin Light Chain 12A Human, Recombinant

Synonyms

Myosin regulatory light chain 12A, MLC-2B, Myosin RLC, Myosin regulatory light chain 2 nonsarcomeric, Myosin regulatory light chain MRLC3, MYL12A, MLCB, MRLC3, RLC, MRCL3, MYL2B.

Myosin regulatory light chain 12A (MYL12A) has a vital role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. The MYL12A protein is involved in cytokinesis, receptor capping, and cell locomotion.

Description

MYL12A Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 195 amino acids (1-171 a.a.) and having a molecular mass of 22.4kDa. MYL12A is fused to a 24 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

Escherichia coli

Physical Appearance

Sterile Filtered colorless solution.

Formulation

MYL12A protein solution (0.25mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol and 1mM DTT.

Stability

Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MGSHMSSKRT KTKTKKRPQR ATSNVFAMFD QSQIQEFKEA FNMIDQNRDG FIDKEDLHDM LASLGKNPTD EYLDAMMNEA PGPINFTMFL TMFGEKLNGT DPEDVIRNAF ACFDEEATGT IQEDYLRELL TTMGDRFTDE EVDELYREAP IDKKGNFNYI EFTRILKHGA KDKDD

Usage

Bio-world products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.