RAB4A, Member RAS Oncogene Family Human, Recombinant

Synonyms

Ras-related protein Rab-4A, RAB4A, RAB4, HRES-1/RAB4.

RAB4A is a member of the small GTPase superfamily. RAB4A interacts with STX4, RAB11FIP1, RABEP1, CD2AP and KIF3B. In addition, Rab4 is involved in the translocation of glucose transporter (Glu4) in adipocytes in response to insulin. Rab4 overexpression causes a redistribution of receptors on plasma membrane versus endocytic compartments.

Description

RAB4A produced in E. coli is a single, non-glycosylated polypeptide chain containing 238 amino acids (1-218 a.a) and having a molecular mass of 26.5kDa. RAB4A is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.

Source

E. coli

Physical Appearance

Sterile Filtered colorless solution.

Formulation

RAB4A protein solution (1mg/ml) containing 20mM Tris-HCl buffer (pH8.0), 20% glycerol, 0.1M NaCl and 1mM DTT.

Stability

RAB4A Human Recombinant although stable at 4°C for 1 week, should be stored below -18°C. Please prevent freeze thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSH MSQTAMSETY DFLFKFLVIG NAGTGKSCLL HQFIEKKFKD DSNHTIGVEF GSKIINVGGK YVKLQIWDTA GQERFRSVTR SYYRGAAGAL LVYDITSRET YNALTNWLTD ARMLASQNIV IILCGNKKDL DADREVTFLE ASRFAQENEL MFLETSALTG ENVEEAFVQC ARKILNKIES GELDPERMGS GIQYGDAALR QLRSPRRAQA PNAQECGC

Usage

Bio-world products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

RAB11A Human, RAB1A Human, RAB1B Human, RAB21 Human, RAB27A Human, RAB27B Human, RAB2A Human, RAB3A Human, RAB3D Human, RAB5A Human, RAB5B Human, RAB6A Human, RAB6B Human, RAB7A Human