S100 Calcium Binding Protein A2 Human, Recombinant

Synonyms

Protein S100-A2, CAN19, Protein S-100L, S100 calcium-binding protein A2, S100A2, S100L, MGC111539.

S100A2 belongs to the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100A2 may function as a modulator against excess calcium accumulation in normal human mammary epithelial cells and also have a role in suppressing tumor cell growth. S100A2 may have a tumor suppressor function. S100 family members are localized in the cytoplasm and/or nucleus of a wide range of cells, and are involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. Chromosomal rearrangements and altered expression of the S100A2 gene are implicated in breast cancer.

Description

S100A2 Human Recombinant fused with a 20 amino acid His tag at N-terminus produced in E. coli is a single, non-glycosylated, polypeptide chain containing 117 amino acids (1-97 a.a.) and having a molecular mass of 13.1kDa. The S100A2 is purified by proprietary chromatographic techniques.

Source

Escherichia coli

Physical Appearance

Sterile Filtered colorless solution.

Formulation

The S100A2 solution (1 mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 5mM DTT, 30% glycerol and 0.2M NaCl.

Stability

S100A2 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

Amino acid sequence

MGSSHHHHHH SSGLVPRGSHMCSSLEQALA VLVTTFHKYS CQEGDKFKLS KGEMKELLHK ELPSFVGEKV DEEGLKKLMG SLDENSDQQV DFQEYAVFLA LITVMCNDFF QGCPDRP

Usage

Bio-world products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

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S100A1 Human, S100A10 Human, S100A11 Human, S100A12 Human, S100A13 Human, S100A14 Human, S100A16 Human, S100A3 Human, S100A4 Human, S100A4 Human, His, S100A5 Human, S100A6 Human, S100A6 Mouse, S100A7 Human, S100A7A Human, S100A8 Human, S100A8 Human, His, S100A9 Human, His