Close

Description

Synonyms

S100 calcium-binding protein A7 (psoriasin 1), S100A7c, PSOR1.

S100A7 is a member of the S-100 family of calcium binding proteins and is produced through a non-classical secretory pathway to the cytoplasm. S100A7 takes part in the regulation of several cellular courses, such as cell cycle, cell progression and cellular differentiation. S100A7 holds two EF-hand domains and is extremely upregulated in psoriatic epidermis, in addition to bladder squamous cell carcinoma and breast cancer tissue, signifying a probable part in carcinogenesis.

Description

S100A7 Human Recombinant produced in E. coli is a single, non-glycosylated polypeptide chain containing 121 amino acids (1-101) and having a molecular mass of 13.6 kDa. The S100A4 is fused to a 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques.

Source

Escherichia coli

Physical Appearance

Sterile Filtered clear solution.

Formulation

S100A7 protein at 0.5mg/ml in 20mM Tris-HCl, pH-8, 0.1M NaCl, 1mM DTT and 30% Glycerol.

Stability

Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months. Please prevent freeze-thaw cycles.

Amino Acid Sequence

MGSSHHHHHH SSGLVPRGSH MSNTQAERSI IGMIDMFHKY TRRDDKIDKP SLLTMMKENFPNFLSACDKK GTNYLADVFE KKDKNEDKKI DFSEFLSLLG DIATDYHKQS HGAAPCSGGS Q

Usage

Bio-world products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.

Related Products

S100A1 Human, S100A10 Human, S100A11 Human, S100A12 Human, S100A13 Human, S100A14 Human, S100A16 Human, S100A2 Human, S100A3 Human, S100A4 Human, S100A4 Human, His, S100A5 Human, S100A6 Human, S100A6 Mouse, S100A7A Human, S100A8 Human, S100A8 Human, His, S100A9 Human, His

Properties

Storage Temperature

-20°C

Purity

Greater than 95.0% as determined by SDS-PAGE