Bacitracin from Bacillus subtilis

Bacitracin, is a small cyclic polypeptide that binds to dolichol-PP preventing its dephosphorylation to dolichol-P, which is needed to build the oligosaccharide.Bacitracin disrupts Gram-positive bacteria by interfering with cell wall and peptidoglycan synthesis. Unlike other oral administrative drugs, bacitracin is primarily used as a topical preparation as it can cause kidney damage. Bacitracin interferes with the dephosphorylation of bactoprenol, a membrane carrier molecule that transports the building blocks of the peptidoglycan bacterial cell wall outside of the inner membrane.

• Approximately 75,000 units/gm
• Protect from moisture
• Do not breath dust and avoid contact with skin and eyes
• For in vitro lab use only. Not for human use or consumption

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