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Description

FUDR, or 5-Fluorodeoxyuridine, is an antiproliferative agent shown to have work against a variety of neoplasms. It inhibits DNA synthesis by prior inhibition of thymidylate synthetase, and has been prescribed as a treatment for several liver and colon cancers.

FUDR can be a powerful cancer treatment when combined with Mitomycin C and 5-Fluorouracil. Floxuridine is soluble in aqueous solutions up to 50 mg/mL.

bioWORLD is committed to providing only the best when it comes to cancer research. We have spent more than 25 years perfecting our Separopore® agarose beads and GlycoMatrix™ lectins.


bioWORLD's products are supplied for LABORATORY RESEARCH USE ONLY. The product may not be used as a drug, agricultural or pesticidal product, food additive or as a household chemical.

References

See "Mechanisms of cell death induced by 5-fluoro-2'-deoxyuridine (FUdR)--necrosis or apoptosis after treated with FUdR" and "Five-minute treatments with fluorouracil, floxuridine, and mitomycin have long-term effects on human Tenon's capsule fibroblasts" by Pubmed.

Properties

Shelf life

4 years

Storage Temperature

-20°C

European Com.#

200-072-5

Purity

>98%

Appearance color

White to off-white

Appearance form

Powder

Molecular Formula

C9H11FN2O5

Molecular Weight

246.19 g/mol

Density

1.64 g/cm3 (Predicted)

Melting point

147.8 °C

Boiling point

519.54 °C (Predicted)

Solubility (@ RT)

H2O: 50 mg/mL
Isopropanol: 1:43
Methanol: 1:7
DMSO: 49 mg/mL at 25°C
Ethanol: 10 mg/mL at 25°C
Soluble in acetone. Insoluble in ether, benzene, and chloroform.