N-Acetyl-D-Galactosamine Separopore® 4B-CL

Applications:

N-Acetyl-D-galactosamine-Separopore® 4B-CL is an agarose affinity chromatography matrix used to purify carbohydrate-binding proteins such as membrane receptors, and also lectins with affinity to N-Acetyl-galactosamine. N-Acetyl-D-galactosamine-Separopore® 4B-CL has been used to study periodontal disease and to facilitate the design of potent small-molecule ice recrystallization inhibitors. N-Acetyl-D-galactosamine-Separopore® 4B-CL has also been used to demonstrate a molecular shuttle between extracellular and cytoplasmic space allowing for monitoring of GAG biosynthesis.

Note: Separopore® is a cost-effective equivalent to Sepharose® in all of its physical properties and binding characteristics.

References

Deactivation of Soybean Agglutinin by Enzymatic and Other Physical Treatments. J Agric Food Chem. (2010) (In Press).
Characterization and purification of the discoidin domain-containing protein retinoschisin and its interaction with galactose. Biochemistry. (2008) 47: 9098-106.
Isolation and characterization of the localized adherence factor of enteropathogenic Escherichia coli. Infect Immun. (1988) 56: 2979-83.